![]() Although multiple commercial clear aligner systems are available today globally, the use of clear thermoformed plastic materials for clear aligner fabrication remains a common feature. ĬAT typically comprises a series of clear plastic trays covering the dentition with a snug fit, that is to be used by the patient at all times except eating and brushing and generally changed sequentially every one to two weeks to accomplish planned orthodontic tooth movements. A recent survey carried out across North America also indicated that more orthodontists in the younger generations believe that clear aligners will be the main technique to treat malocclusions. The global clear aligners market size was projected to increase from USD 3.1 billion in 2021 to USD 11.6 billion in 2027 with a compound annual growth rate (CAGR) of 13%. The demand for CAT has increased significantly over the last decade, presumably due to aggressive marketing strategies by commercial clear aligner companies that employ direct-to-consumer advertising as well as widespread utilization of various social media channels, thereby generating heightened public awareness for esthetic orthodontic treatment alternatives, especially for the adult patients. With the rapid technological improvements in biomaterials, computer-aided design (CAD) and manufacturing (CAM), clear aligner therapy (CAT) has emerged as a promising alternative to conventional fixed appliances (FAs) in orthodontics. Finally, while innovations in aligner materials such as shape memory polymers, direct three-dimensional (3D) printed clear aligners and bioactive materials combined with clear aligner materials are essential to further advance the applications of CAT increased awareness of environmental responsibilities among aligner manufacturers, aligner prescribing clinicians and aligner users is essential for better alignment of our climate change goals towards a sustainable planet. Advances in aligner material chemistry and engineering possess the potential to bring about radical transformations in the therapeutic applications of CAT in the absence of which, clear aligners would continue to underperform clinically, due to their inherent biomechanical constraints. Historical developments and current protocols in aligner fabrication, features of contemporary bioactive materials, and emerging trends related to CAT are discussed. This narrative review has attempted to comprehensively encompass the entire gamut of materials currently used for the fabrication of clear aligners and elucidate their characteristics that are crucial in determining their performance in an oral environment. In the case of non-resident importers with addresses outside of Canada, the postal code is left blank.Rapid technological improvements in biomaterials, computer-aided design (CAD) and manufacturing (CAM) have endorsed clear aligner therapy (CAT) as a mainstay of orthodontic treatment, and the materials employed for aligner fabrication play an all-important role in determining the clinical performance of clear aligners. The importer is not necessarily the end-user of the product. ![]() This list does not include individuals or importers whose importer numbers are unavailable. The 'Major Importers' listed comprise those which collectively account for up to 80% of all imports (in terms of $ value) for the selected city. Confidentiality rules prohibit the release of the information. ![]() No report is available for the parameters you specified. PATTERSON DENTAL CANADA INC/PATTERSON DENTAIRE CANADA INC
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